(FIT)-Module 4 Workshop 7: Electrocradiogrpahic and Electrophysiological Correlations, Atrial Fibrillation, Clinical Scenarios and Syndromes-Poole Case 2 Answer

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Video Summary

The patient has Long QT Syndrome type 3 (LQT3) with a prolonged QT interval of 525 ms. The QT interval lengthens at slower heart rates, especially risky during sleep due to possible Torsades de Pointes. Although beta-blockers are first-line treatments, mexilatine is used to reduce sudden death risk by shortening repolarization through blocking the late inward sodium current. Other medications (A, C, D) are incorrect as they prolong the QT interval. Quinidine is specifically used in Brugada syndrome, not LQT3. Thus, mexilatine (B) is the appropriate treatment choice for this patient.

Keywords

Long QT Syndrome type 3

prolonged QT interval

mexilatine

beta-blockers

Torsades de Pointes