(FIT)-Module 4 Lectures: Non-Invasive Diagnosis and Treatment-Antiarrhythmic Drugs, Part 2

Video Transcription

Video Summary

The video focuses on practice questions designed for board exam preparation regarding the use of anti-arrhythmic drugs, emphasizing decision-making in various clinical scenarios. In one case, a pregnant woman with PSVT is correctly treated with adenosine followed by sotalol, highlighting the importance of FDA safety categories for medications during pregnancy. Another case discusses a patient starting on dronetarone, advising a reduction in digoxin dose due to interaction via PGP. Quinidine is highlighted for its benefit in Brugada syndrome, and rinolazine is suggested for Long QT syndrome type 3 due to its sodium current blocking properties. Amiodarone dose reduction is recommended when neurological toxicity is suspected. Lastly, interactions with herbal supplements and potential drug modifications, such as simvastatin replacement due to CYP3A4 inhibition, are discussed to avoid adverse effects when combining certain drugs, like rifampin, with anti-arrhythmics.

Keywords

anti-arrhythmic drugs

pregnancy and medication safety

drug interactions with digoxin

Brugada syndrome treatment

Long QT syndrome management