(FIT)-Module 4 Lectures: Non-Invasive Diagnosis and Treatment-Biophysics of Catheter Ablation (Gerstenfeld)

Video Transcription

Video Summary

Ed Gerstenfeld's lecture on "Core Concepts of Electrophysiology" focuses on the biophysics of catheter ablation, a critical area not often emphasized in training programs. The presentation covers various ablation techniques including radiofrequency (RF) ablation, which uses high-frequency energy to heat tissue, cryoablation, and the emerging technique of pulse field ablation. <br /><br />For RF ablation, the lecture explains the processes of resistive and conductive heating, discussing how heat penetrates tissue and forms lesions and the importance of achieving a myocardial temperature above 50 degrees Celsius for irreversible damage. Advances in RF technology, such as irrigated RF electrodes, enable more power delivery by cooling the electrode-tissue interface, although they carry risks like steam pops if overheated. <br /><br />Cryoablation, contrastingly, causes tissue destruction through freezing, offering reversible effects that make it advantageous near critical structures like the heart's conduction system. Lastly, pulse field ablation, which employs non-thermal electrical pulses, is highlighted for its selective tissue damage and reduced risk to structures like the esophagus or nerves, positioning it as a promising option for atrial fibrillation treatment. Gerstenfeld underscores the importance of understanding these biophysical principles for effective and safe ablation procedures.

Keywords

Electrophysiology

Catheter ablation

Radiofrequency ablation

Cryoablation

Pulse field ablation

Biophysics

Myocardial temperature

Atrial fibrillation