HRS Board Review 2025 New Courses (Reviewers Copy)-Workshop 1_Tomaselli_2025

Video Transcription

Video Summary

In this clinical scenario, for managing stress-induced polymorphic PDCs likely due to CPVT in a pregnant woman, the recommendation is to increase the dose of Nadolol and monitor PVCs. This approach is based on genetic evidence linking her condition to a mutation found in her deceased sister. Other options, like limited flecainide use, are considered safe later in pregnancy and postpartum. Calcium channel blockers should be avoided due to fetal risks, and ICD use is complex, possibly acting as both therapy and trigger. Overall, guidelines for heritable arrhythmias during pregnancy are sparse, often relying on long QT syndrome protocols.

Keywords

CPVT

Nadolol

pregnancy

heritable arrhythmias

long QT syndrome