Inside EP: Insights From Clinical Decision-Makers for the Industry Professional-Pathophysiology of Heart Failure

Video Transcription

Video Summary

The speaker begins the presentation by expressing gratitude and acknowledging the audience for attending despite the challenges they faced. They explain that the goal of their talk is to discuss the pathophysiology of heart failure, the importance of conduction defects, pacing strategies to prevent heart failure progression and reduce sudden cardiac death, and individualizing electrical therapies for treating heart failure. They emphasize that LVADs and transplants are not the solution and that the costs of treating heart failure are increasing exponentially. They outline the changes that occur in the heart as it fails and emphasize the importance of understanding the electromechanical interface. They discuss the different types of heart failure, HEF-PEF and HEF-REF, highlighting their different pathophysiology and treatment strategies. They also mention the relationship between heart failure and atrial fibrillation, as well as the risk of sudden cardiac death in patients with low ejection fraction. They touch on the efficacy of resynchronization therapy in non-ischemic patients, the importance of individualizing therapy, and the potential of new pacing strategies and neuromodulation techniques.

Asset Caption

Jagmeet P. Singh, MD, PhD, FHRS, Massachusetts General Hospital, Boston, MA

Keywords

heart failure

conduction defects

pacing strategies

sudden cardiac death

individualizing electrical therapies

LVADs