The Lead Episode 107: A Discussion of Catheter Ablation of AFib Patients with Cardiac Amyloidosis and Sarcoidosis: Procedural Outcomes and Findings LIVE from Heart Rhythm 2025-The Lead Episode 107 Live from HRS (video)

The Lead Episode 107 Live from HRS (video)

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Video Summary

In this episode of The Lead at HRS 2025, Dr. Prash Sanders and colleagues discuss a paper on catheter ablation of atrial fibrillation (AF) in patients with cardiac amyloidosis and sarcoidosis. The study from the University of Pennsylvania analyzed procedural outcomes in over 3,500 patients, identifying 41 with these infiltrative cardiomyopathies. Findings showed higher atrial arrhythmia recurrence in amyloid patients linked to low voltage areas in the atria, highlighting a need for tailored ablation strategies and possible combination with pharmacological treatments. The discussion also emphasized the increasing detection of amyloid cases.

Keywords

catheter ablation

atrial fibrillation

cardiac amyloidosis

sarcoidosis

infiltrative cardiomyopathies