The Lead Episode 127: A Discussion of Remote Screening for Asymptomatic Atrial Fibrillation: The AMALFI Randomized Clinical Trial, LIVE at HRX 2025-A Discussion of Remote Screening for Asymptomatic Atrial Fibrillation: The AMALFI Randomized Clinical Trial (Speaker Information)

A Discussion of Remote Screening for Asymptomatic Atrial Fibrillation: The AMALFI Randomized Clinical Trial (Speaker Information)

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The document summarizes a discussion on the AMALFI randomized clinical trial, which investigated remote screening for asymptomatic atrial fibrillation (AF). Hosted by Melissa E. Middeldorp, MPH, PhD (University of Adelaide), the discussion featured contributions from Dr. Emma Svennberg (Karolinska Institutet and University Hospital) and Dr. Rod S. Passman (Northwestern University). The original trial was authored by a multidisciplinary team led by Rohan Wijesurendra and published in JAMA.<br /><br />The AMALFI trial focused on the feasibility and impact of remotely screening individuals without symptoms for atrial fibrillation—a common heart rhythm disorder that can increase stroke risk if left undetected. Remote screening may enable earlier detection and treatment, potentially improving clinical outcomes. The discussion likely explored the trial’s methodology, findings, and implications for clinical practice, especially regarding the effectiveness of digital or telehealth approaches to AF screening.<br /><br />The key contributors disclosed their affiliations and potential conflicts of interest, including industry ties and research funding from pharmaceutical and medical device companies, illustrating transparency in the presentation.<br /><br />Overall, the discussion emphasized the importance of innovative screening strategies for silent atrial fibrillation and evaluated the AMALFI trial’s contribution to understanding how remote monitoring might be integrated into broader cardiovascular care. The expert panel provided insights into future directions and challenges in adopting remote AF detection methods to reduce stroke burden through timely diagnosis and management.

Keywords

AMALFI trial

remote screening

asymptomatic atrial fibrillation

atrial fibrillation detection

stroke risk

digital health

telehealth

clinical outcomes

cardiovascular care

remote monitoring