The Lead Episode 56: Durability of Pulmonary Vein Isolation Using Pulsed-Field Ablation-JACC: CLINICAL ELECTROPHYSIOLOGY (visual aid)

JACC: CLINICAL ELECTROPHYSIOLOGY (visual aid)

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The study analyzed the durability of pulmonary vein isolation (PVI) using pulsed-field ablation (PFA) in patients with arrhythmia recurrence after an index PVI. The results of the study, which included 1,184 patients, showed that durable isolation was observed in 71% of the pulmonary veins during the redo procedure, and 38% of patients showed durable isolation of all veins. Reconnections were most frequently found on the anterior aspect of the upper veins and on the inferior aspect of the right lower vein. Prior operator experience with cryoballoon ablation was associated with a higher rate of PVI durability compared to operators with only point-by-point radiofrequency experience. The study highlights the potential of PFA for lasting PVI and the importance of operator experience and technique in achieving durable lesion outcomes.

Keywords

pulmonary vein isolation

pulsed-field ablation

arrhythmia recurrence

redo procedure

reconnections

operator experience

cryoballoon ablation

radiofrequency ablation

lesion outcomes

durable isolation