The Lead Episode 77: A Discussion of Pulmonary Vein Isolation vs Sham Intervention in Symptomatic Atrial Fibrillation-The Lead Episode 77 Video

Video Transcription

Video Summary

Dr. Janice Chu, a cardiac electrophysiologist, hosts a discussion with Dr. Prash Sunders and Dr. Chris Chung about the SHAM-PVI randomized clinical trial presented at the European Society of Cardiology Congress and published in JAMA. The trial involved 126 AFib patients, comparing the effects of pulmonary vein isolation (PVI) via cryoablation and a sham procedure. Both procedures showed a reduction in AFib burden but more significant with PVI. Despite the logistical and blinding challenges in the sham-controlled study, improvements in AFib burden and quality-of-life post-ablation were noted. Limitations such as study size and duration were highlighted. The session concluded that further studies are needed to build on these findings, affirming the benefits of AFib ablation.

Keywords

SHAM-PVI trial

AFib ablation

pulmonary vein isolation

cryoablation

quality-of-life