Unbreak My Heart: Progress Towards Personalized Arrhythmia Treatment-Generation of Mature Cardiomyocytes from Pluripotent Stem Cells (Presenter: Yoshinori Yoshida, MD, PhD)

Generation of Mature Cardiomyocytes from Pluripotent Stem Cells (Presenter: Yoshinori Yoshida, MD, PhD)

Video Transcription

Video Summary

The video transcript discusses the use of IPS technology to generate cancer cells from patients and transform them into cardiomyocytes. By exploiting the changes that occur in these cells, new drugs can be detected through frequent screening. The transcript then focuses on the process of efficiently generating cardiomyocytes and removing unwanted cancer cells generated by these cardiomyocytes. This is achieved through the use of RNA technology, specifically microRNA switch technology, to differentiate cardiomyocytes from non-cardiomyocytes. The transcript also mentions the use of fluorescence protein and max sorting systems to further clean and sort the cardiomyocytes. The effectiveness of these methods is validated through various tests and analysis, showcasing high percentages of purified cardiomyocytes. Overall, the transcript highlights the importance of generating and purifying cardiomyocytes for further research and drug development.

Meta Tag

Lecture ID 16356

Location Room 213

Presenter Yoshinori Yoshida, MD, PhD

Role Invited Speaker

Session Date and Time May 10, 2019 10:30 AM - 12:00 PM

Session Number S-053

Keywords

IPS technology

cancer cells

cardiomyocytes

RNA technology

drug development