(FIT)-Module 1, Workshop 1: Electrocardiographic/Electrophysiologic Correlation-Tomaselli Case 12 Question

Tomaselli Case 12 Question

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Question 12. Activation maps recorded from normal and failing myocardium are shown in this figure. The changes in conduction are most likely the result of which of the following? Downregulation of delayed rectifier potassium current and action potential prolongation, downregulation of beta-adrenergic receptors, downregulation of connexin 43, or downregulation of sodium-calcium exchange. Let me give you a few seconds to consider this.

Keywords

activation maps

myocardium

conduction changes

connexin 43 downregulation

heart failure