(FIT)-Module 1, Workshop 1: Electrocardiographic/Electrophysiologic Correlation-Tomaselli Case 7 Question

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Video Summary

A 51-year-old woman with syncope, hypertension, and a history of substance use disorder is on hydrochlorothiazide, nifedipine, and methadone. Her key lab findings are a magnesium level of 2.3 mg/dL and a low potassium level of 3.3 mEq/L. An echocardiogram shows left ventricular hypertrophy and a normal ejection fraction. The likely cause of her arrhythmia, as observed on an ECG she had shortly after admission, is related to hypokalemia induced by hydrochlorothiazide, potentially worsened by drug-induced QT prolongation.

Keywords

syncope

hypokalemia

hydrochlorothiazide

QT prolongation

left ventricular hypertrophy