#HRS2025 YIA Competition - Basic Science Finalists

Description

The Young Investigator Award (YIA) Competition will give attendees a broad exposure to the latest methods of electrophysiology research.

Learning Objectives

Learn about the consequences of dysregulation of adrenergic response.
Learn about the high throughput screens for genotype-specific therapeutics for channelopathies.
Learn about suppression-replacement gene therapy for short QT 1.

Session Chair(s)

Eugenio Cingolani, MD
Faisal Syed, BS, MBChB
Marina Cerrone, MD
Mark Levin, MD
Ravi Ranjan, MD, PhD

Presentation

Exercise-induced dysregulation of the adrenergic response in a mouse model of PKP2-arrhythmogenic cardiomyopathy
Presenter(s): Lilian Gutierrez, MSci, PhD, Chantal JM. van Opbergen, Mingliang Zhang, Sarah Boyce, Giorgia Bertoli, PhD, Yan Deng, Michael Cammer, Fenxa Liang, Mario Delmar, MD, PhD

High throughput screens identify genotype-specific therapeutics for channelopathies
Presenter(s): Christian Egly, PharmD, PhD, Alex Shen, Tri Do, Suah Woo, Matthew Ku, Brian P. Delisle, PhD, Brett Kroncke, PhD, Bjorn C. Knollmann, MD, PhD

KCNH2 Suppression-Replacement Gene Therapy for Type 1 Short QT Syndrome (SQT1): A Proof-of-Concept Efficacy Trial in Rabbits with SQT1
Presenter(s): Saranda Nimani, MD, Sahej Bains, BS, Nicolò Alerni, Balázs Ördög, András Horváth, Julien Louradour, Lucilla Giammarino, David Tester, BS, Ruben Lopez, Miriam Barbieri, Olgica Beslac, Manuel Egle, Nicolas Christoforou, Varjany Vashanthakumar, Lluis Matas, Stefanie Perez-Feliz, Chiara Parodi, Luisana Gisela Garcia Casalta, Changsung John. Kim, PhD, Wei Zhou, MD, Dan Ye, MD, Jacqulyn Jurgensen, Michael A. Barry, Mariana Bego, Lisa Keyes, Jane Owens, Jason Pinkstaff, Manfred Zehender, Michael Brunner, Daniela Casoni, Fabien Praz, Andreas Haeberlin, Gabriel Brooks, MA, MD, Michael John. Ackerman, MD, PhD, Katja E. Odening, MD

Disclosures

Lilian Gutierrez: