Description
These selected oral abstracts are focused on emerging mechanisms of atrial arrhythmias.
Learning Objectives
- Describe novel mechanisms of atrial arrythmias.
- Appreciate how structural and functional changes contribute to atrial arrhythmogenesis.
- Summarize molecular determinants of atrial arrhythmias.
Session Chair(s)
Edward Vigmond, PhD
Presentation
Diabetes and hypomagnesemia promote atrial fibrillation risk by TRPM7-mediated activation of inflammation, oxidative stress, and SR diastolic Ca2+ leak
Presenter(s): Man Liu, PhD, Hong Liu, Mitchell C. Neumann, Xiaoxu Zhou, Samuel C. Dudley, MD, PhD
Structural Determinants of Re-entrant Driver Dynamics in Atrial Fibrillation: Insights from Digital Twins of Ex-vivo Human Hearts
Presenter(s): Anuradha Kulathilaka, Roshan Sharma, James Kennelly, Bruce H. Smaill, PhD, Mark L. Trew, PhD, Vadim V. Fedorov, PhD, Jichao Zhao, PhD
Hedgehog Pathway: A Novel Regulator in Atrial Fibrillation Pathogenesis.
Presenter(s): James Nicholas. Kezos, PhD, Sofia Guernouche, Hajira MOKHTAR, Georg Vogler, Elodie Morel, PhD, CGC, Gilles Millat, Elodie Planchais, Rolf Bodmer, MD, Karen Ocorr, PhD, Philippe Chevalier, MD
Atrial fibrillation susceptibility gene ErbB4 contributes to pathologic atrial remodeling
Presenter(s): Naoko Yamaguchi, MD, PhD, John Santucci, Charlotte J. Casdin, Peter S. Park, Xianming Lin, Konstantin Kahnert, Florencia Schlamp, Alexander Ferrena, John Barnard, BS, PhD, Alicia Lundby, PhD, Mina K. Chung, MD, David R. Van Wagoner, PhD, David S. Park, MD, PhD
Non-Sustained Ventricular Tachycardia (NSVT) on 14-day Zio Monitor in Previously Healthy Pediatric Population
Presenter(s): Jonathan Smerling, MD, Shankar Baskar, MD, Chad Connor, MD, David S. Spar, MD, Timothy K. Knilans, MD, Richard J. Czosek, MD
Disclosures
Man Liu:
- Nothing Relevant to Disclose
Jichao Zhao:
- Nothing Relevant to Disclose
Hajira MOKHTAR:
- Nothing Relevant to Disclose
Naoko Yamaguchi:
- Nothing Relevant to Disclose
Jonathan Smerling:
- Nothing Relevant to Disclose
To view all Heart Rhythm 2025 Faculty Disclosures, please click
here.
Education Framework
General Concepts
-- Pathophysiological Basis of Cardiac Arrhythmias and Basic EP
-- 4. Know abnormalities of cardiac electrophysiology, including altered ion channel function (inherited and drug-induced) and their effect on action potentials.