Basic Mechanisms and Effects of Pulsed Field Ablation

Description

This session will review effects of different PFA delivery, present the most contemporary mechanism(s) of PFA myocardial injury and revise beneficial and detrimental effects of myocardial and non-myocardial tissues.

Learning Objectives

Summarize the mechanisms of myocardial cell injury from electroporation with PFA.
Describe differences in injury between myocardial and non-myocardial tissue.
Review beneficial effects of different PFA delivery protocols and future applications.

Session Chair(s)

Nishaki Mehta, MD
Samuel Asirvatham, MD

Presentation

Mechanisms of Cell Injury By Electroporation in Cardiac vs Non-cardiac Tissue
Presenter(s): Bor Kos

Tissue and Animal Models of Cardiac Injury and Nearby Organs with Pulse Field Ablation
Presenter(s): Leonid Maizels, MD, PhD

Different PFA Protocols and Delivery Tools to Maximize Myocardial Injury and Minimize Extracardiac Tissue Injury
Presenter(s): Gurukripa N. Kowlgi, MBBS, MSci

Future Technology and Applications of Electroporation in EP
Presenter(s): Damijan Miklavcic, PhD

Disclosures

Bor Kos:

Medtronic,Inc. (Honoraria/Speaking/Consulting Fee - Consulting)

Leonid Maizels:

Nothing Relevant to Disclose

Gurukripa Kowlgi:

Nothing Relevant to Disclose

Damijan Miklavcic:

Medtronic,Inc. (Honoraria/Speaking/Consulting Fee - Consulting)
Medtronic,Inc. (Research (Contracted Grants for PIs and Named Investigators only) - Independent Contractor (including contracted research))

To view all Heart Rhythm 2025 Faculty Disclosures, please click here.

Education Framework

General Concepts
-- Pathophysiological Basis of Cardiac Arrhythmias and Basic EP
-- 8. Know the biophysics of radiofrequency ablation, cryoablation, electroporation and other energy sources.

Summary


Availability:	No future session


Cost:	FREE


Credit Offered:	No Credit Offered

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