The session will focus on presenting the main inflammatory cardiomyopathies subtypes (Myocarditis; Sarcoidosis; DSP-Cardiomyopathy) and the arrhythmic risk, the risk stratifying strategies, and the currently therapies available (pharmacological and invasive) for each one of these substrates.

• Outline the importance of cardiac inflammation as a cause of cardiac arrhythmias across a wide spectrum of inherited and acquired cardiac conditions.
• Review the differences in arrhythmic risk stratification and ICD implantation practices required for common subgroups of inflammatory cardiomyopathies.
• Summarize data on VT ablation and cutting edge therapies modulating the arrhythmic risk for inflammatory cardiomyopathy.

Alessio Gasperetti, MD, PhD
Jordana Kron, MD

Myocarditis, Inflammation, and Arrhythmias
Presenter(s): Giovanni Peretto, MD, PhD

Sarcoidosis, Inflammation, and Arrhythmias
Presenter(s): Jonathan Chrispin, MD

Desmoplakin Cardiomyopathy, Inflammation, and Arrhythmias
Presenter(s): Cynthia A. James, PhD, CGC

Inflammatory Cardiomyopathy and VT Ablation
Presenter(s): Pasquale Santangeli, MD, PhD

Sport, Arrhythmia and Inflammatory Cardiomyopathy
Presenter(s): Rachel Lampert, MD

Giovanni Peretto:

• Abbott (Honoraria/Speaking/Consulting Fee - Speaking and Teaching)

Jonathan Chrispin:

• Biosense Webster, Inc. (Honoraria/Speaking/Consulting Fee - Consulting)
• Abbott Medical (Honoraria/Speaking/Consulting Fee - Speaking and Teaching)
• Boston Scientific (Honoraria/Speaking/Consulting Fee - Speaking and Teaching)

Cynthia James:

• Lexeo, Inc. (Research (Contracted Grants for PIs and Named Investigators only) - Research)
• Pfizer, Inc. (Honoraria/Speaking/Consulting Fee - Consulting)
• StrideBio (Research (Contracted Grants for PIs and Named Investigators only) - Research)
• ARVADA Therapeutics (Research (Contracted Grants for PIs and Named Investigators only) - Research)

Pasquale Santangeli:

• Biosense Webster, Inc. (Honoraria/Speaking/Consulting Fee - Speaking and Teaching)
• Abbott (Honoraria/Speaking/Consulting Fee - Consulting)
• Medtronic (Honoraria/Speaking/Consulting Fee - Speaking and Teaching)
• Biotronik (Honoraria/Speaking/Consulting Fee - Speaking and Teaching)
• Boston Scientific (Honoraria/Speaking/Consulting Fee - Speaking and Teaching)

Rachel Lampert:

• Nothing Relevant to Disclose

To view all Heart Rhythm 2025 Faculty Disclosures, please click here.

Ventricular Tachyarrhythmias
   --   Ventricular Fibrillation (VF) and SCA/SCD
      --   213. Know treatment strategies for protecting from and preventing recurrent ventricular fibrillation depending on the underlying etiology.

Other Arrhythmia Syndromes
   --   Arrhythmogenic Cardiomyopathies
      --   269. Know the broad spectrum of genetic, systemic, infectious, and inflammatory disorders that make up the arrhythmogenic cardiomyopathies, including hypertrophic cardiomyopathy, arrhythmogenic right/left ventricular cardiomyopathy, cardiac amyloidosis, sarcoidosis, Chagas Disease, left ventricular noncompaction and muscular dystrophies.

Other Arrhythmia Syndromes
   --   Arrhythmogenic Cardiomyopathies
      --   277. Know the methods to manage patients with arrhythmogenic cardiomyopathies, including the pharmacotherapy, ablation, lifestyle modifications and device therapy.