Description
These selected oral abstracts are focused on the development of novel anti-arrhythmic therapies.
Learning Objectives
- Describe emerging anti-arrhythmic treatments.
- Appreciate novel molecular therapeutic targets.
- Outline alternative approaches to anti-arrhythmic therapy.
Session Chair(s)
Steven Poelzing, PhD
Presentation
Restoration of Ventricular Electrical Synchrony via cBIN1 Gene Therapy in a Canine Model of Ischemic Cardiomyopathy
Presenter(s): Kyoichiro Yazaki, MD, PhD, Muhammad Shuja. Khan, MS, PhD, Emmanuel Offei, BS, MS, Sofia Ruiz. Castillo, Ankur R. Shah, MS, PhD, Ava Yektaeian Vaziri, Douglas R. Smego, Ravi Ranjan, MD, PhD, TingTing Hong, MD, PhD, Robin M. Shaw, Derek J. Dosdall, PhD
Unlocking Sodium-Glucose Co-transporter 2 Inhibitor’s Potential: Reducing Arrhythmias and Ion Channel Remodeling in Cardiorenal Syndrome
Presenter(s): Shin-Huei Liu, MD, PhD, Li-Wei Lo, MD, PhD, Yu-Hui Chou, MS, Wei-Lun Lin, PhD, Yenn-Jiang Lin, MD, PhD, Shih-Lin Chang, MD, PhD, Yu-Feng Hu, MD, PhD, Fa-Po Chung, MD, PhD, Shih-Ann Chen, MD
Therapeutic Effects of Anti-CD14 Antibody in Arrhythmogenic Cardiomyopathy
Presenter(s): Stephen P. Chelko, PhD, Waleed Farra, Vinay Penna, Emily Shiel, BS, Ann Marie. Centner, BS, MS, PhD, Elisa Cannon, KORY LAVINE, Jeffrey E. Saffitz, MD, PhD
Immunomodulatory effects of transcutaneous vagus nerve stimulation in heart failure with preserved ejection fraction
Presenter(s): Thamizhiniyan Venkatesan, PhD, Maria Toumpourleka, Lynsie Morris, Seabrook Whyte, MS, Kurt Zimmerman, Stavros Stavrakis, MD, PhD
AAV-HCN4t-mediated biological pacing as a potential life-saving therapy for congenital complete heart block
Presenter(s): Jianan Wang, MS, Evelien Birza, Timo Jonker, Ruud Visser, Rinske Sparrius, Mischa Klerk, Arnie Boender, Hee Young Lee, Kyung Ho Park, Larry Park, Joyce Visser, Marlijn Jansen, osne kirzner, Joost Sluijter, Saskia de Jager, Klaus Neef, Veronique Meijborg, Hanno Tan, Vincent M. Christoffels, PhD, Gerard J. Boink, MD, MSci, PhD
Disclosures
Kyoichiro Yazaki:
- Nothing Relevant to Disclose
Shin-Huei Liu:
- Nothing Relevant to Disclose
Stephen Chelko:
- Implicit BioScience (Research (Contracted Grants for PIs and Named Investigators only) - Research)
Thamizhiniyan Venkatesan:
- Nothing Relevant to Disclose
Gerard Boink:
- PacingCure (Ownership/Partnership/Principal - Management Position)
To view all Heart Rhythm 2025 Faculty Disclosures, please click
here.
Education Framework
General Concepts
-- Pathophysiological Basis of Cardiac Arrhythmias and Basic EP
-- 3. Know normal basic cardiac electrophysiology, including the phases and currents that drive the action potential in different cardiac tissues.