Recent Insights Into the Structure and Function of Cardiac Ion Channels

Description

This session will highlight recent insights into the structure, function, and pharmacological targeting of ion channels and the implications they hold for our understanding of cardiac physiology in health and disease as well as our ability to treat cardiac arrhythmia.

Learning Objectives

Describe recent developments in ion channel structural biology.
Discover newly recognized biophysical behaviors of cardiac ion channels.
Summarize ways to exploit new insights for therapeutic targeting of cardiac ion channels.

Session Chair(s)

Przemyslaw Radwanski, PharmD, PhD
Rengasayee Veeraraghavan, PhD

Presentation

Atomic Resolution Structure of the Cardiac Voltage-gated Sodium Channel, Na_V1.5
Presenter(s): Krishna Chinthalapudi

Surprising New Properties of Connexin Hemichannels: Implications for Cardiovascular Physiology
Presenter(s): Jorge Contreras

From Structural Biology to Rational Drug Design: Engineering Safe Ways to Target Sodium Channels
Presenter(s): Igor Vorobyov

How Cardiac Rhythms Rewire the Heart Over the Long Run
Presenter(s): Nicolae Moise, MD

Disclosures

Krishna Chinthalapudi:

Nothing Relevant to Disclose

Jorge Contreras:

Nothing Relevant to Disclose

Igor Vorobyov:

Nothing Relevant to Disclose

Nicolae Moise:

Nothing Relevant to Disclose

To view all Heart Rhythm 2025 Faculty Disclosures, please click here.

Education Framework

General Concepts
-- Pathophysiological Basis of Cardiac Arrhythmias and Basic EP
-- 3. Know normal basic cardiac electrophysiology, including the phases and currents that drive the action potential in different cardiac tissues.

Summary


Availability:	No future session


Cost:	FREE


Credit Offered:	No Credit Offered