OasisLMS

In this episode of The Lead, host Cinzia Monaco, MD, PhD, is joined by Kinan Kneizeh, MD,  and Konstantinos Vlachos, MD, PhD, to discuss “Pulsed Field Ablation Versus Sham to Treat Atrial Fibrillation: The PFA-SHAM Randomized Clinical Trial.” The panel examines the trial’s sham-controlled evidence for the effects of pulsed field ablation on atrial fibrillation recurrence, quality of life, AF burden, and psychological well-being, while considering placebo effects, study limitations, and the applicability of the findings to clinical practice.

• Describe the design, patient population, endpoints, and key findings of the PFA-SHAM randomized clinical trial.
• Evaluate the effects of pulsed field ablation compared with a sham procedure on atrial fibrillation recurrence, AF burden, quality of life, and psychological well-being.
• Assess the trial’s limitations, potential placebo effects, and applicability to the management of patients with symptomatic atrial fibrillation.

Host: Cinzia Monaco, MD, PhD

Guests: Kinan Kneizeh, MD and Konstantinos Vlachos, MD, PhD

C. Monaco

• No relevant disclosures

K. Kneizeh

• No relevant disclosures

K. Vlachos

• No relevant disclosures

Staff Disclosure(s) (note: HRS staff are NOT in control of educational content. Disclosures are provided solely for full transparency to the learner):