The Lead Episode 110: A Discussion of Left Bundle Branch Area Pacing in Hypertrophied Hearts: The Ex-Vivo Ovine Model to Study Deployment of Pacing Leads in Thick Septum LIVE from Heart Rhythm 2025 in San Diego

Description

Left Bundle Area Pacing in Hypertrophied Hearts: An Ex Vivo Ovine Model to Study Deployment of Pacing Leads in Thick Septum describes the development of a novel ex vivo sheep heart model with induced septal hypertrophy to simulate challenging left bundle branch area pacing (LBBAP) scenarios. The study evaluates the deployment characteristics and fixation behavior of pacing leads in thickened septal tissue, aiming to improve procedural safety and lead placement strategies in patients with left ventricular hypertrophy. This model offers a valuable tool for preclinical testing and refinement of lead technologies and techniques.

Learning Objectives

Evaluate the deployment characteristics and fixation behavior of pacing leads in thickened septal tissue
Determine how to improve procedural safety and lead placement strategies in patients with left ventricular hypertrophy

Article Authors and Podcast Contributors

Article Authors

- Darius Chapman
- Calvin Muenzinger
- Alexis Puvrez
- Jonathan P. Ariyaratnam
- Mohanaraj Jayakumar
- Mohamed Abbas
- Monika M. Gawalko
- Alessandra Pina
- Shaun Evans
- Jenish P. Shroff
- Abhinav B. Anand
- Christopher X. Wong
- Rajeev K. Pathak
- Prashanthan Sanders

Podcast Contributors

Deep Chandh Raja, MBBS, MD, PhD, Australian National University, Kauvery Hospital
Parikshit S. Sharma, MD, MPH, FHRS, Cleveland Clinic Florida

Faculty and Disclosures

All relevant financial relationships have been mitigated.

Host Disclosure(s):

D. Raja:
Nothing to disclose.

P. Sharma:
Honoraria/Speaking/Consulting: Medtronic, Abbott, Biotronik

Staff Disclosure(s) (note: HRS staff are NOT in control of educational content. Disclosures are provided solely for full transparency to the learner):
S. Sailor: No relevant financial relationships with ineligible companies to disclose.
S. Colbert: No relevant financial relationships with ineligible companies to disclose.

Summary

Availability:

On-Demand

Cost:

FREE

Credit Offered:

No Credit Offered